
Quick Answer
Yes, you need antimalarial medication for Mozambique. Malaria is present year-round, including tourist areas. Take Malarone, doxycycline, or mefloquine as prescribed. Also use DEET repellent, wear long sleeves at dusk, and sleep under mosquito nets.
Short Answer
Yes, you need antimalarial medication for Mozambique. The country is a year-round malaria risk zone, including in tourist areas like Maputo, Tofo, and Vilanculos. The risk is highest November-April (rainy season) and lowest May-October, but transmission occurs throughout the year.
Recommended Medications
- Atovaquone-proguanil (Malarone): Best tolerated, most expensive. Start 1-2 days before travel, daily during trip, 7 days after.
- Doxycycline: Cheaper, effective. Start 1-2 days before, daily during trip, 4 weeks after. Can cause sun sensitivity.
- Mefloquine (Lariam): Weekly dose. Can cause vivid dreams and anxiety. Not recommended for people with psychiatric history.
Prevention Beyond Medication
- DEET 30-50% repellent (apply every 4-6 hours)
- Permethrin-treated clothing
- Long sleeves and trousers at dawn/dusk
- Air-conditioned or screened rooms
- Mosquito nets (provided by most lodges)
If You Get Sick
Seek medical attention immediately. Symptoms: fever, chills, headache, muscle pain (appears 7-30 days after bite). Maputo private clinics: Clinica Cruz Azul, Polana Medical Center.
September 2, 2026
Frequently Asked Questions
Yes. Mozambique is a year-round malaria-risk country, including popular destinations such as Maputo, Tofo, and Vilanculos. Consult a healthcare professional before traveling to choose the right antimalarial medication.